Category Archives: Medical

Endocrine cells in the brain impact the optimization of behavior

4An individual exposed to stress can usually rapidly adapt the own behavior to the specific situation. Biochemical messenger substances in the brain play a central role in this rapid transformation process. We know that hormones additionally have a stress regulating function, but that their effects are more slowly apparent. Using a combination of optical and genetic techniques, the research team has had the capacity to show that corticotrophs, the cell populations that prompts the adrenal cortex and produce the stress hormones of the hypothalamic-pituitary-adrenal axis, will quickly impact avoidance behavior immediately after the onset of a stress situation. This insight could add to the development of effective treatments which will facilitate the management of acute stress induced reactions or may even have the capacity to mitigate acute stress associated conditions.

The human body is controlled by the hormonal system and the nervous system. The hypothalamus situated in the middle of the basis of the brain has a key role here providing the link between the body and the different regions of the brain similarly as directly and indirectly controlling a progression of essential physiological vegetative functions. In addition, it is the most important control organ of the human endocrine system, because it regulates when and how much of a hormone is produced. Both the hypothalamus and its production of hormone are also subject to the impacts of emotional stress. The pituitary gland is connected to the hypothalamus and together they form a single functional unit called the hypothalamic-pituitary-adrenal axis.

Hormones secreted by the hypothalamus incorporate the supposed releasing hormones, such as the corticotropin-releasing hormone. This stimulates the production of the adrenocorticotropic hormone in the pituitary gland. The adrenocorticotropic hormone is a hormone secreted by the anterior lobe of the pituitary and it regulates the production of other hormones, such as the stress hormone cortisol.

It can be basically assumed that the neurotransmitters of the CNS quickly determine whether fight or flight behavior is to develop in a given situation. To date, medical science has conjectured that the stress-regulating effects of the hormones of the HPA axis come into play far more slowly. Stress researchers found it very problematic to establish the concrete role of the hypothalamic-pituitary-adrenal axis in the rapid adaptation of behavior in a stress situation in more detail in standard animal models. This is because the location of the pituitary gland and hypothalamus in mammals makes them difficult to access. To overcome these obstacles, the researcher decided to create an innovative optogenetic research technique. They managed to develop a hereditarily modified zebrafish larva in which they had the capacity to manipulate the activity of the HPA axis using light and subsequently observe the resultant changes to the responses of the altered cells.

The researchers introduced a synthetic enzyme into their animal model that elevates the levels of the intracellular messenger substance cyclic adenosine monophosphate (cAMP) only in the corticotropic cells of the hypothalamic-pituitary-adrenal axis. Their rise is important for the release of hormones in the corticotropic cells of the anterior pituitary. The levels of the resulting so-called transgenetic animal stress hormones can be increased by means of exposure to light. This means the researchers can thus observe the accompanying changes to behavior.

The recently published research results that the corticotropic cells in the pituitary become directly active on the beginning of a stress situation that is seen as distressing. These then influence locomotion and avoidance behavior as well as the sensitivity to the stimulus. The specialists translate this as proof that the corticotropic cells in the pituitary play a significant role in the rapid adaptation of behavior to local environments identified as antagonistic.

Can Rehabilitation get your life back on track after treatment for a mental illness?

2 The treatment of mental health disorders usually comprises two aspects: the actual treatment itself, and rehabilitation. Treatment emphases on reducing the symptoms of an illness that are present in the patient. In the case of a person with fever, the goal of treatment is to bring down the body temperature.

Types of treatment:

Psychiatric rehabilitation is a part of treatment that emphases on helping the person get back to an ideal level of functioning and to reach their life goals which is brought by providing medical, psychological and social input. There is no limit between treatment and rehabilitation.

Why is rehabilitation necessary?

 People suffering with severe and chronic psychiatric illnesses such as bipolar disorder and schizophrenia may be mentally disabled by their condition and require rehabilitation to pick up basic skills. In the case of disorders such as mental retardation, a process of habilitation is followed to help patients learn skills necessary for daily functioning.

Psychiatric rehabilitation services may include:

  • Community Residential Services
  • Workplace Accommodations
  • Supported Employment or Education
  • Social Firms
  • Assertive Community Treatment Teams Assisting with Social Service Agencies
  • Medication Management
  • Programs
  • Employment
  • Family Issues
  • Coping Skills
  • Activities of Daily Living and Socializing

Psychiatric rehabilitation focuses to help individuals with persistent and serious mental illness to develop the emotional, social and intellectual skills needed to live, learn and work in the community with the least amount of professional support.

Go Natural to Lower Cholesterol & High Blood Pressure!

1Natural treatments for heart disease often aim to control cholesterol levels, lower blood pressure, and improve heart health. Generally, research on such treatments is limited, compared to conventional medical treatments.

Few natural sources have clinically proven to reduce cholesterol. There’s no evidence that alternative therapies lower the risk of heart failure. However, many people have experienced success with alternative treatments.

Types of Cholesterol:

There are two kinds of cholesterol:

  • Low-density lipoprotein (LDL), also called “bad” cholesterol
  • High-density lipoprotein (HDL), also called “good” cholesterol

 Cholesterol Levels:

Usually, normal human should have low levels of LDL and higher levels of HDL. The recommended cholesterol levels are:

  • Total cholesterol: less than 200 mg/dL
  • LDL cholesterol: less than 100 mg/dL
  • HDL cholesterol: 50 mg/dL or higher

Natural Remedies:

The ingredients in some alternative therapies can interfere with certain medications or have harmful side effects.

Few regularly used organic products which may prone to reduce cholesterol are;

  • Astragalus
  • Hawthorn
  • Flaxseed
  • Fish with omega-3 fatty acids
  • Garlic
  • Red yeast rice
  • Plant sterol and stanol supplements

 Benefits of natural remedies

  • No prescription required
  • Can be implemented along with standard treatment plan 

Drawbacks of natural remedies

  • No clinical evidence
  • Side effects may occur

 Medications for high cholesterol

A variety of medications are also available to lower high cholesterol. Usually prescribed medications are,

  • Statins such as lovaststin or atorvastatin
  • Cholestyramine
  • Injectable medications like volocumab

 Blood Pressure

Blood pressure is association of systolic and diastolic pressure. Systolic pressure represents BP, while the heart is pumping and diastolic pressure stands for BP when the heart is at rest.

High blood pressure (hypertension) occurs when the pressure on the arteries and blood vessels becomes too high and the arterial wall becomes distorted causing extra stress on the heart.

Long term hypertension increases the risk of stroke, heart attack and diabetes.

Blood pressure ranges:

  • Normal: Less than 120/80 mm Hg
  • Prehypertension: Systolic pressure between 120–129 and diastolic pressure less than 80
  • Stage 1 Hypertension: Systolic pressure between 130–139 or diastolic pressure between 80–89
  • Stage 2 Hypertension: Systolic pressure at least 140 or diastolic pressure at least 90 mm Hg

Outcomes of high blood pressure:

  • Arterial damage
  • Aneurysm
  • Metabolic syndrome
  • Reduced kidney function
  • Heart failure
  • Blocked or ruptured blood vessels
  • Vision loss
  • Loss of cognitive function

Causes of high blood pressure:

  • A high-salt diet
  • Obesity
  • Emotional stress
  • Birth control pills
  • Alcohol
  • Caffeine
  • Smoking
  • Heavy-metal poisoning

Natural Ways to Lower Blood Pressure

  • Flax seeds
  • Fish oil supplement
  • Magnesium supplements
  • Potassium supplements
  • Omega-3 foods
  • Foods That Reduce Blood Pressure:
  • Dark chocolate
  • Garlic
  • Spinach
  • Sunflower Seeds
  • Bananas
  • Tomatoes
  • Broccoli
  • Melon

Be sure to know more about Hypoplastic Left Heart Disorder (HLHS)

11At the point when a child is determined to have basic aortic stenosis that is in danger for advancing to hypoplastic left heart disorder (HLHS) in utero. Hypoplastic left heart disorder (HLHS) is an intricate and uncommon heart imperfection present during childbirth in which the left half of a tyke’s heart is seriously immature.

The doctors can play out a method called fetal aortic valvuloplasty.

The method utilizes a needle and a minor inflatable to develop the tight aortic valve to build blood course through the left half of the fetal heart, which will prompt improved left heart work and advance typical left-sided heart development.

On the off chance that untreated, basic aortic stenosis and HLHS can be deadly. By playing out this system before birth, it can advance improved development of the left-sided heart structures and lead to less medical procedures after birth.

Atrial septal stenting:

At the point when a baby has hypoplastic left heart disorder (HLHS) with prohibitive or unblemished atrial septum, the doctors can play out this fetal method to diminish the high mortality related with this mix of injuries.

In this method, the chamber septum is additionally opened with stents, which decompresses and permits blood from the lungs and left upper heart chamber (left chamber) to stream back to the correct side of the heart.

This counteracts harm to the baby’s lungs, diminishes weight in the left chamber and enables the fetal lungs to grow regularly.

Just 50 percent of children with HLHS with unblemished atrial septum get by to return home after birth. This fetal technique offers any expectation of limiting the danger or conceivably tiring condition influencing the baby, serving to both encourage safe conveyance and possibly improving long haul results of the tyke.

These intercessions were impractical 20 years prior. The researchers are proceeding to break new hindrances with fetal heart intercessions.

Is Digital Health The Future Of Healthcare?

2Digital healthcare can give to people the opportunity provided with ‘smart care’ in a homely environment, so that they can live an independent lifestyle. Caregivers can be provided with adequate resources and tools to be able to manage care services effectively and efficiently, people can be monitored in the comfort of their own home. Digital health encompasses many sub-sectors includes, mobile-health, telehealth, health information technology and telemedicine, main goal, to make the digital health revolution a reality. Global healthcare sector is at the intersection of ever-rising costs and introducing innovations in disruptive digital innovations, digital health innovations.

Disciplines in Digital Health

  • Mobile Health (m-Health): It is a general term for the practice of medicine and care delivery which is supported by the use of mobile phones and other wireless technology. With increased access to mobile technology m-Health offers the potential to promote better health and help people to achieve a healthier lifestyle. It can be helpful to reduce costs by improving efficiencies in the health and care systems. Mobile-Health can be applied on the streams of education, diagnostic support, helplines as well as remote monitoring and data collection
  • Health Information Technology (HIT): It is applied to health and health care settings. As the health information management is computerised data will be secured in the process of exchange health information between patients and medical experts
  • Telehealth: It is a broad spectrum of technologies and systems around the remote exchange of data between a patient and their clinician and approaches can assist in diagnosis and monitoring based upon the typically used support patients with long term conditions
  • Telemedicine: It is a term for offering remote care using telecommunication and information technologies. It can help to overcome distance obstacles and accessible to medical services that may not be routinely available to remote communities
  • Personalised Medicine: It is an emerging practice of medicine that moves us away from the one-size-fits-all approach. It also brings closer to a more precise for the powerful approach to healthcare which is customised to the individual needs

Conclusion

Everyday technologies like cell phones, smartphones, sensors, cloud storage systems, and data analytics are playing a critical role in digital health today. The use of digital health will help in early disease prediction that will lead to behavioural changes that prevent and eliminate system costs. Patients will be able to compare quality and prices based on value, which will improve productivity. Timelier identification of diseases will enhance treatment and can reduce waste. In 2018, the global digital health market was at $179.6 billion, according to Transparency Market Research (TMR). Growth in this market is anticipated to rise at a CAGR of 13.4% between 2019 and 2025, reaching $536.6 billion by the end of 2025.

INITIAL ANNOUNCEMENT OF 14th WORLD CONGRESS ON INDUSTRIAL HEALTHCARE AND MEDICAL TOURISM

Past Conference Report | Brochure Download | Call for Abstracts

ME Conferences take privilege to invite you to attend “14th World Congress on Industrial Healthcare and Medical Tourism” scheduled to be held during July 18-19, 2019 at  Abu Dhabi, UAE with the theme “Linking Healthcare, Tourism & Economy”.

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Health Congress 2019 forecasts existence of keynote speeches, session speeches, delegates, young researchers and students around the world. This conference perhaps a giant event that creates an ideal platform to share expertise addressing current advancements involved in Industrial Healthcare and Medical Tourism. It will be a wonderful opportunity for all the delegates as it provides an international networking opportunity to collaborate with the world class Industrial Healthcare and Medical Tourism societies and associations.

Conference Sessions:

  • Global Healthcare Economics
  • Digital Healthcare
  • Nursing and Healthcare
  • Public Health & Community Medicine
  • Oral care & Dental Health
  • Disease Prevention
  • Nutrition & Obesity
  • Diabetic Healthcare
  • Skin & Body Health
  • Cardiovascular Health
  • Women’s Health, Gynaecology & Obstetrics
  • Neonatal & Paediatric Healthcare
  • Infectious & Emerging Diseases
  • Mental and Physical Health
  • Pharmaceutics and Healthcare
  • Alternative Healthcare and Case Studies
  • Healthcare and Innovations
  • Medical Tourism
  • Challenges Involved in Medical Tourism
  • Environmental Impact of Medical Tourism

Book Mark your Dates for “14th World Congress on Industrial Healthcare and Medical Tourism” in Abu Dhabi, UAE for more recent updates in Digital Industrial Healthcare and Medical Tourism System.

For more details contact:

Ava Cassandra

Program Manager | Health Congress 2019

Tel: +1-201-380-5561 Ext: 7005

Mail: healthcare@mehealthevents.org

Website: https://healthcare.global-summit.com/middleeast/

Take a closer look on the Omega 3 supplements

1Premature birth is the main source of death for kids under 5 years of age around the world, representing near one million deaths every year. Premature infants are at higher danger of a scope of long time conditions including visual hindrance, formative postponement and learning troubles.

Premature birth is a basic worldwide medical problem, with an expected 15 million infants brought into the world too soon every year

“While the length of most pregnancies is somewhere in the range of 38 and 42 weeks, untimely children are those conceived before the 37-week point – and the prior an infant is conceived, the more noteworthy the danger of death or weakness.”2

The long-chain omega-3 fats and their job in lessening the danger of untimely births – especially Docosahexaenoic corrosive (DHA) and Eicosapentaenoic corrosive (EPA) found in greasy fish and fish oil supplements. They saw 70 randomized preliminaries and found that for pregnant ladies, expanding the everyday admission of long-chain omega-3s:

  • Lowers the danger of having an premature infant (under 37 weeks) by 11% (from 134 for each 1000 to 119 for every 1000 births)
  • Lowers the danger of having an early premature infant (under 34 weeks) by 42% (from 46 for each 1000 to 27 for every 1000 births)
  • Reduces the danger of having a little infant (under 2500g) by 10%

“There are relatively few choices for preventing untimely birth, so these new discoveries are vital for pregnant ladies, babies and the well being experts who care for them. The cause of premature babies is not discovered yet, so anticipating and avoiding early birth has always been a risk of test. This is one reason omega-3 supplementation in pregnancy is of such extraordinary enthusiasm to scientists around the globe.”

Epilepsy research links mossy brain cells to memory loss and seizures

A minor group of cells in the brain can have a big consequence on seizures and memory in a mouse model of epilepsy. Concurring to a novel study in Discipline, deficiency of mossy cells may be a factor to raging seizures in temporal lobe epilepsy (TLE) and also memory problems often experienced by individuals with the disease.

The function of mossy cells in epilepsy has been wrangled about for decades. This study uncovers how significant these cells are in the disease, and the research indicates that avoiding loss of mossy cells or discovering methods to activate them may be potential therapeutic targets. Mossy cells, named for the dense moss-like protrusions that mask their surface, are situated in the hippocampus, a brain region that is known to play key roles in remembrance. Loss of mossy cells is linked with TLE, but it is unidentified what role that plays in the disease. By means of state-of-the-art tools, researchers were able to turn mossy cells on and off to trail their impacts in a mouse model of epilepsy.

EPI2019 (2)

The remarkable Research carried out by manipulating certain brain cells in the hippocampus of a mouse model. Utilizing 21st-century devices brings us closer than always to opening the puzzles after this devastating disorder.TLE, numerous seizures, acknowledged as focal seizures, start off in one part of the brain and are evident on electroencephalography (EEG) checks that show the brain’s electrical action. These seizures can consequence in symptoms such as jerking or a strange taste or smell, and many individuals with TLE might not be alert that these indications are for seizures. In some cases, focal seizures can extend all through the complete brain becoming generalized, ensuing in spontaneous muscle spasms, or shakings, that distress the limbs and other parts of the body as well as loss of consciousness.

When Researchers unit identified focal seizures on the mice’s EEG checks, they regulated mossy cells on or off to observe whether they had any consequence on the seizures. The researchers found that turning on the cells avoided the focal seizures from transitioning into raging ones. After the mossy cells were turned off, though, raging seizures were more likely to occur. Mossy cells had barely a negligible effect on the incidence of focal seizures. This was the initial time they e were capable to illustrate in particular that mossy cell action can dominate convulsive seizures. These mice were missing most of their mossy cells, yet we were able to see effects just by controlling the tiny number of existing cells.

Individuals with TLE often encounter temporary changes in thoughts and long-term issues with memory. Study on the role of mossy cells in two explicit types of memory: object recognition and spatial memory, which refers to recognizing where objects are situated and exploring in the vicinity of the surroundings. In these tests, the mice were put in a chamber among two duplicate items. The next day, one of the objects was supplanted with another one (to test for object recognition) or stirred to a different location (to test for spatial memory). The epileptic mice had difficulty with spatial memory assignments but their capability to recognize items was unchanged. In addition, turning off mossy cells in healthy mice too driven to issues with spatial memory in those creatures. These conclusions propose that a reduction in mossy cells can lead to convulsive seizures as well as memory shortfalls.

Further research is obligatory to advance comprehend the function of mossy cells in seizure development as well as their impacts at the beginning of the disease.

Maternal–Fetal and Neonatal Medicine

Maternal-fetal medicine is also called as Perinatology; it is one division of medicine that targeting on handling health care of the mother and fetus prior to, during pregnancy and after pregnancy. And Neonatology is a sub-branch of medicine of the new-born infants. Especially this branch consists of the medical care to newborns and ill newborns. It is completely hospital-based treatment. It is usually known as neonatal intensive care units.

Maternal-fetal and neonatal medicine specialists are physicians who subspecialize within the field of obstetrics, gynaecology and paediatrics. They act as both consultants during lower-risk pregnancy and as the primary obstetrician in especially high-risk pregnancies. After birth, they may interest to work closely with neonatologists or paediatricians.

pregnancy

The scope of practice:       

Maternal-fetal and neonatal medicine specialists attend to patients who fall within certain levels of maternal care. These levels correspond to health risks for the mother, new-baby or both, during pregnancy. They take care of pregnant women have chronic conditions (kidney or heart disease, diabetes, hypertension, and thrombophilia), pregnant women who are all at risk for pregnancy complications (pre-eclampsia, preterm labor and twin or triplet pregnancies), and pregnant women with fetuses at risk. Fetuses may be at risk due to congenital abnormalities or chromosomal, infections, genetic diseases maternal disease and growth restriction.

Mothers with chronic conditions, such as blood pressure, drug use before or during pregnancy, or a diagnosed medical condition may require a consult with a maternal-fetal specialist. In addition, pregnant women who experience difficulty conceiving may be referred to a maternal-fetal specialist for assistance.

We cordially invite you to attend the International Conference on Maternal, Fetal and Neonatal Medicine 2019. It is provides a great platform to explore concepts with topics that include Fetal and Maternal Physiology, Neonatology and Perinatology, Maternal-Fetal Imaging, Maternal & Child Care, Nursing & Maternal-Fetal Medicine, Midwifery & Nursing, Multiple Pregnancies, Neonatal Oncology, Fetal Neurology, Neonatal Cardiology & Pulmonology, Neonatal Endocrinology, Neonatal Gastroenterology, Surgery and Radiology, Pregnancy and Childbirth.

A novel diagnostic device with Simple test detects disease-carrying mosquitoes, presence of bio pesticide

A novel diagnostic device has been developed by researchers that can effortlessly, rapidly and cheaply distinguish whether a mosquito belongs to the species that carry dangerous diseases such as Zika virus, dengue, chikungunya or yellow fever. It can also reveal whether the bug has come into contact with a mosquito-control strategy acknowledged as Wolbachia. Several of these diseases are scattering in areas where they weren’t common earlier than. Having surveillance is significant in concurrence with any kind of outburst, and this way allows a quick est in the area.

Mosquito AbatementThe device uses a smartphone camera, a small 3D-printed box, and a basic chemical examination to demonstrate whether a dead mosquito belongs to the Aedes aegypti variety. Aedes aegypti carries Zika and other distressing viruses that torment an estimated 100 million inhabitants around the world each year. The species, in addition, is closely connected to the tripling of cases of mosquito-borne infections in the United States since 2004.The device created by scientists and students also detects the existence of a biopesticide called Wolbachia, a type of bacteria that keeps mosquitoes from dissemination of diseases. In countries around the world and in 20 U.S. states where the Aedes aegypti mosquito is established, scientists working in public health agencies have started to infect mosquitoes with Wolbachia by introducing the bacteria into a local mosquito population to help control the spread of viruses.Because mosquitoes show no outward signs of having the bacteria – and because existing diagnostic tests are hard to read, expensive and logistically cumbersome – the new tool represents a significant step forward for those hoping to monitor the effectiveness of Wolbachia.This test can happen without including a lot of staff and equipment to make sure Wolbachia is effectual and distribution as anticipated.simpletestde

Public health groups confine and kill mosquitoes regularly in conjunction with observing efforts, but existing technology requires a complex process to extricate nucleic acid from within mosquitoes, frequently after they have been deceased for days and have begun to perish, leading to the larger expense and the chance of more errors in lab tests than the new equipmentimages . The new diagnostic tool uses a smartphone’s camera and a basic test that can be done anyplace. It tests mosquitoes’ nucleic acid with no requiring a complicated procedure to eradicate it. Legitimately known as a loop-mediated isothermal amplification and oligonucleotide strand dislocation, or Lamp OSD, the probe conveys a simple yes-or-no readout on a cellphone, by accurateness of greater than 97 percent.

In addition to the tests to identify mosquito species and Wolbachia, the team also is exploring the use of the innovation to easily recognize whether caught mosquitoes are carrying Zika, dengue, and other pathogens.