Category Archives: Heart Rhythm

Pediatric cardiology

There is a number of heart conditions that can affect children. Few children have structural differences by birth others involve the electrical system that controls the heartbeat. Pediatric cardiologists mainly treat, diagnose and manage the problems in the child.  Pediatric heart problems in children include congenital heart disease and Arrhythmias. Congenital heart disease refers to heart structural variation by birth in the child which include holes between chambers of the heart, abnormal blood vessels and valve problems. Arrhythmiasis know as abnormal heart rhythms caused by the system that controls the heartbeat electrically. Pediatric cardiologists will treat pulmonary hypertension and systemic hypertension. Systemic hypertension means high blood pressure in the body. But in few regions, pulmonary hypertension is treated by pediatric pulmonologists and systemic hypertension is treated by pediatric nephrologists.

edhgjnIn Food industries generally, Pediatric cardiologists work closely with primary care pediatricians to provide coordinated and comprehensive care. Heart Problems can arise due to various other symptoms in the body so pediatric cardiologist will team up with health care providers. For child care, there are pediatric heart surgeons, cardiac anesthesiologists, neonatologists, cardiac pediatric intensivists, pediatric radiologists, as well as pediatric nurses, nutritionists, and speech, occupational, and physical therapists. There are various Tools to diagnose cardiac conditions in children. Based on Physical and cardiac examination. For Physical examination: Vital signs and Cardiac examination will be carried out. For Laboratory examination: Electrocardiography, Chest X-ray, Pulse oximetry, Blood counts, Echocardiography, Magnetic resonance imaging (MRI and MRA), Computed tomography, Exercise testing, Cardiac catheterization are done. Environmental and genetic conditions associated with heart disease in children also play a major role. There are various Unusual forms of congenital heart disease in children, Unique cardiac conditions in newborn infants, cardiac conditions acquired during childhood, Abnormalities of heart rate and conduction in children and Congestive heart failure in infants and children. For preventing follow the treatment and precautions given by pediatric cardiologist and have a healthy lifestyle

3-Treatments for Heart-Disease that are changing lives

A Drug for Heart Failure: The failure of the heart muscle to forcefully pump blood to the body’s tissues is a common disorder called Congestive heart failure. Heart attacks (stroke), high blood pressure, or diseases that weaken the heart muscle are common causes. The severe shortness of breath or fatigue that limits the ability to enjoy a life of the patients. Paradigm-HF is used in the large clinical trial, the new drug LCZ696 was used to treat heart failure, and it was highly effective. It achieved a substantial 20 % reduction in death or repeat hospitalization compared with the best currently available therapies. Currently, 20 % or more of patients hospitalized for heart failure are readmitted within 30 days which represents a significant burden for patients and the healthcare system.LCZ696 will probably be approved, providing a new, promising option for the 5.7 million Americans with heart failure.

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Treatment for High Cholesterol: The PSCK9 inhibitor is second innovative drug therapy. These specify class of drugs has moved from discovery to the clinic more rapidly than any cardiovascular advancement. The single most important risk factor for developing coronary heart disease is an elevated level of cholesterol, LDL-C. The best drugs for reducing cholesterol, statins, have been shown to lower the risk of heart attack or stroke up to 35%. Statins have been available for 25 + years and have been enormously successful at reducing the burden of heart disease. Patients cannot tolerate statins or can’t take large enough dosages to adequately reduce cholesterol levels. LDL-C will be very high due to a genetic cause, and even the most powerful statins cannot reduce it to safe levels. PSCK9 inhibitors reduce bad LDL-C by as much as 50 % to 70 %. These drugs are given by every 2 weeks or once a month given by very small needles. These can be self-injected by the automated injector. This new class of drugs appears to be well tolerated even in patients who cannot take statins due to adverse effects.

Less Invasive Surgery: In 2011, the FDA approved a new procedure to treat heart valve disease without a major surgical operation, known as Trans-catheter aortic valve replacement (TAVR). This device is approved for who need an aortic valve replacement, but who are too high risk for standard open-heart surgery.

Is there any connection between heart and brain?

Your heart and your brain are more intricately connected than you may realize. Brain signals the heart to pump its oxygen-rich blood through the autonomic nervous system, and heart responds by delivering blood to the entire body, including to brain. If the brain does not receive enough oxygen from the heart, you may experience symptoms ranging from fuzzy thinking to a life-threatening stroke. When blood flow to the brain is interrupted or blocked by a blood clot or plaque that has broken away from an artery or valve and is floating in the bloodstream leads to stroke. The lack of oxygen can cause brain cells to die, leading to symptoms of dementia, disabilities, or even death. The major step to the heart is also ways to protect the brain. The steps to prevent from the stroke: Managing your blood pressure is especially important because high blood pressure is the leading cause of stroke. It also may cause tiny lesions in the brain that can slow your thinking and progress to a loss of brain function in the future.

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Steps to Take during Heart Surgery: When your Heart Surgery includes the valve replacement, it is all the more important to consider ways to protect your brain. Valve replacement procedures, such as transcatheter aortic valve implantation (TAVI), can be life-saving interventions. It will correct restricted blood flow caused by a narrowing or obstruction of the heart valve. However, during valve replacement, small particles of debris can break loose and find their way into the blood vessels of the brain.

What is good for the heart is good for the brain. Understanding the unique relationship between the heart and brain, and taking steps to protect both of these vital organs throughout life, is important for lifelong health.

 

Risk of certain strokes might increase due to high Iron levels

The risk of having a stroke especially the kind that outcomes from a blood clot or other obstacle going from the heart appear by all accounts, to be more prominent in individuals who have larger amounts of iron, as indicated by recent research.

Scientists analyzed stroke risk in individuals for whom they had information on their levels of iron and whether they had genetic contrasts that adjusted their iron status. This yielded proof recommending that those with “genetically determined higher” iron levels were at serious risk of having a stroke.

In addition, it appears that this impact is driven by an expanded danger of cardioembolic stroke, a type of stroke in which blood in a vessel providing the brain is blocked due to an obstruction that has gone from the heart.

According to the World Health Organization (WHO), around 15 million individuals have a stroke each year. Of these, 5 million bites the dust subsequently and another 5 million will be crippled for whatever is left of their lives.

The strokes are major of the ischemic type, which occurs when a blockage in a blood vein has ceased oxygen- and nutrient-rich blood reaching the influenced piece of the brain. Cardioembolic stroke represents an outstanding extent of ischemic strokes and is regularly connected to a heart condition called atrial fibrillation, wherein the heart thumps sporadically and frequently quicker than normal.

Iron has much utilization in the body, the fundamental one being to carry oxygen in RBC. The studies have examined the connection between the iron levels and stroke risk, but the results have been “conflicting.”

Some studies, for instance, have tied a raised danger of stroke to low levels of iron, while others have to fix it to elevated amounts of iron. Furthermore, they have not found any link in the studies.

The researchers explored distinguishing the genetic contrasts of Iron status which impact them. Utilizing a system called Mendelian randomization, the researchers distinguished three “single-letter alterations,” or single nucleotide polymorphisms (SNPs), in their DNA that can raise or lessen a person’s iron status.

They at that point utilized the three SNPs to screen another genetic dataset covering 60,000 individuals who had encountered strokes. They found that individuals with SNPs that can raise iron status were the ones well on the way to have cardioembolic strokes.

They additionally utilized Mendelian randomization to investigate different elements that may affect stroke risk. This uncovered individuals who have more blood platelets, or cells that advance coagulating and stop bleeding, could be at higher hazard for ischemic stroke.

Another examination led to the discovery that individuals low in Factor XI, which is a compound that likewise helps blood clotting, could be at diminished risk of cardioembolic stroke.

Cardiovascular risk –Linked with Yo-yoing weight

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Recent studies alert us with the change of the body weight, BP, Cholesterol, and Diabetes which are associated with the increase of the cardiovascular diseases. These all parameters are known as Health measurements. The researchers wanted to inquire whether any alteration in all the mentioned health measurements would be good predictors or bad predictors of health, which may eventually cause death.

Recently the researchers investigated the health data collected from 6,748,111 people who do not have any Diabetes in their history, and high cholesterol, high BP or Heart attacks at the beginning of their studies. All the people who involved in this study had health check-ups of different types. The information recorded is about all the health measurements (i.e., body weight, systolic blood pressure, cholesterol, and fasting blood sugar).

The researchers concluded that high alteration in these health measurements caused a negative impact on their cardiovascular health. And if a person neglects this alteration and goes on this may be more dangerous as their cardiovascular risk may get higher. Compared with the estimations of the individuals with normal range on an average period of 5 years were healthier. The people whose risk factor developed by 127 percent caused death, 41 percent had a stroke and 43 percent had a heart attack.

Such fluctuations in the health measurements under investigation can be the result of either negative changes or positive changes, according to researches. All got higher. Therefore the researches decided to investigate separately the change in the health measurements whether they have improved or worsened either by 5 %. At last, they found that the cardiovascular risk increased in both the cases that they may cause death.

Doctors should take care of the variability in all the health measurements like BP, Cholesterol, sugar levels as well as body weight.  They should try to stabilize with these parameters so that it would be more helpful for the patients.

By and by, the analysts accentuate that their examination was of an observational nature, implying that they can’t promptly reason that there is a causal connection between the changes and the danger of death and cardiovascular occasions. Moreover, they admit that they didn’t investigate the causes behind the fluctuating body weight, cholesterol, blood .sugar, or pulse. However, a few past investigations on variation were performed in different populaces, recommending that it is probably going to be a typical wonder.

Risk of Varicose Veins may be Predicted by Height

A hereditary investigation of almost a large portion of a million people infers that tallness is not only a connecting factor but rather hidden instrument mechanism varicose veins. Varicose veins otherwise called spider veins are “swollen, curved veins” that can, as a rule, be seen appropriate underneath the skin on a person’s legs. rhy 1

As per the latest estimates, the condition influences around 33 million individuals. The condition is, for the most part, considered very safe, however past investigations have discovered a solid relationship with serious cardiovascular issues, for example, blood thickening and profound vein thrombosis.

Additionally, varicose veins might be tolerably difficult and aesthetically unpleasant to a few people. Presently, an extensive scale genetic investigation distributed in Circulation proposes that a person’s height may decide their danger of treating varicose veins information of 493,519 individuals who were enlisted.

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The investigation confirmed already known hazard factors for varicose vein infection, for example, age, sex, weight, and way of life propensities including smoking and being stationary. Be that as it may, the examination likewise recognized some new risk factors. We affirmed that having had profound vein thrombosis in the past puts you at expanded hazard in the future. Recent inquire about proposes that the opposite seems, by all accounts, to be valid also. Having varicose veins puts you in danger of these blood coagulation.

Of all the new hazard factors identified, the researchers esteemed height as the most astonishing. More prominent stature remained autonomously connected with varicose veins. We were exceptionally shocked to find that height came up from our machine-learning examinations.

Our outcomes strongly recommend height is a reason, not only a connecting factor but rather a fundamental instrument prompting varicose veins. By directing the biggest genetic study at any point performed for varicose vein sickness, we currently have a greatly improved comprehension of the science that is changed in individuals in danger for the ailment. Qualities that foresee a person’s height might be at the foundation of this connection between height and varicose veins and may give intimations to treating the condition.

 The ongoing investigation additionally recognized 30 qualities that are attached to varicose veins, as well as to profound vein thrombosis. Varicose vein illness is extraordinarily pervasive yet shockingly little is thought about the science. There are no restorative treatments that can forestall it or turn around it once it’s there. We’re trusting that with this new data, we can make new treatments, as our investigation features a few qualities that may speak to new translational targets.

Early Sign of Heart Disease- Forehead Wrinkles

Wrinkles are a truly inevitable element of the aging process, yet rather than concentrating on concealing the wrinkles, new research focuses on another motivation to give careful consideration to them. It turns out further than-typical temple wrinkles may demonstrate terrible news for heart wellbeing.

 In an investigation including in excess of 3,200 members, scientists found that various forehead wrinkles are related with an expanded danger of heart disease, the main source of death for the two people. In the wake of following the members for a long time, it turned out to be evident that those with some forehead lines were five times more prone to die due to heart disease, while those with numerous profound wrinkles were 10 times more inclined to bite the dust of coronary illness contrasted with those with no brow wrinkles at all.

12If we just have forehead wrinkles that do not mean we are at risk. That simply indicates us to check for the symptoms. We cannot see or feel risk factors caused by high cholesterol or High BP. We will look at them as a marker as they are visible and are simple. If a person is with a potential cardiovascular risk, they have to check classical risk factors like blood pressure as well as lipid and blood glucose levels.

Atherosclerosis occurs, when the arteries solidify because of an expansion in plaque, may clarify the relationship among wrinkles and coronary illness especially on the grounds that oxidative pressure and changes in collagen protein assume a job in the two highlights. Since it’s the first run through this association has been made, future examinations should burrow further to completely affirm the discoveries. In any case, for the time being, hold onto your wrinkles as a free and simple approach to hold your well-being under control. At the point when plaque gathers inside the arteries, heart disease and even heart assaults may guarantee. Some of the main risk factors for atherosclerosis incorporate smoking, elevated cholesterol levels, insulin obstruction, hypertension, physical idleness, age, and a family history of coronary illness. 13

You don’t need to sit tight for profound temple wrinkles to fly up to alarm you of coronary illness, however: There are a lot of protection estimates you can take currently to help bring down your hazard. The factors like not smoking or utilizing tobacco, managing with your stress through things like meditation, exercising for somewhere around 30 minutes most long stretches of the week, getting seven to nine long periods of rest each night, and eating heart-solid eating regimen wealthy in natural products, veggies, and entire grains and low in wellsprings of soaked and trans fats, similar to red meat, browned nourishment, and dairy items could help keep your heart sound for a considerable length of time to come.